Drug Testing

Drug Testing

Does your firm require drug and controlled substance abuse testing? Alliance proudly serves all industries with state-of-the-art drug testing services, including electronic chain of custody and monitoring. Alliance prides itself on working with clients to ensure that the entire investigative process is seamless and compliant.

Alliance Worldwide Investigative Group offers the following drug screening services:

  • Random Drug Screening
  • Pre-employment Drug Screening
  • Reasonable Suspicion
  • Post-Accident
  • Return to Work

Drug testing comes in three forms:  urine, hair and blood. We offer hair and urine testing in either 5 – 9 – or 10 panel drug screenings at either Labcorp or Quest.

C O M M O N   D R U G   T E S T I N G   P A N E L S

5-Panel

    Urine Drug Testing

Hair Test

Hair Test plus Oxy

Oral Fluid Testing

9-Panel

Urine Drug Testing

Hair Test Plus Oxy

Oral Fluid Testing

10-Panel

Urine Drug Testing

12-Panel Hair Test

Alcohol Testing

Urine Alcohol Drug Test

Breath Alcohol Test

Blood Alcohol Test

ETG Hair Test (For Long Term Alcohol Use)

Amphetamines Amphetamines Amphetamines
Cocaine Benzodiazepines Benzodiazepines
Marijuana Barbiturates Barbiturates
Opiates Cocaine Cocaine
Phencyclidine Marijuana Marijuana
Methadone Methadone
Opiates Methaqualone
Phencyclidine Opiates
Propoxyphene Phencyclidine
Propoxyphene

Drug Descriptions

 5 panel drugs

COC (Cocaine) derived from the leaves of the coca plant, is a potent central nervous system stimulant and a local anesthetic. Cocaine induces euphoria, confidence and a sense of increased energy in the user; these psychological effects are accompanied by increased heart rate, dilation of the pupils, fever, tremors and sweating. Cocaine is used by smoking, intravenous, intranasal or oral administration, and excreted in the urine primarily as benzoylecgonine in a short time. Benzoylecgonine has a longer biological half-life (5-8 hours) than cocaine (0.5-1.5 hours) and can generally be detected for 24-80 hours after cocaine use or exposure.

AMP (Amphetamine) is class of potent sympathomimetic agents with therapeutic applications. They are chemically related to the human body’s natural catecholamine, epinephrine and norepinephrine. Acute higher doses lead to enhanced stimulation of the central nervous system and induce euphoria, alertness, reduced appetite, and a sense of increased energy and power. More acute responses produce anxiety, paranoia, hallucinations, and psychotic behavior. The effects of amphetamines generally last 2-4 hours following use, and the drug has a half-life of 4-24 hours in the body. About 30% of amphetamines are excreted in the urine in unchanged form, with the remainder as hydroxylated and deaminated derivatives.

Opiates (Analgesics) comprise a large group of substances, which control pain by depressing the central nervous system. Morphine is the prototype compound of this group. Morphine is excreted in the urine primarily as morphine-3-glucuronide while smaller amounts are excreted as unchanged free morphine and other metabolites. It is also the major metabolic product of codeine and heroin. Morphine is delectable in the urine for several days after an opiate dose.

THC (9-Tetrahydrocannabinol – Marijuana) is the primary active ingredient in cannabinoids (marijuana). When ingested or smoked, it produces euphoric effects. Users have impairment of short-term memory and THC use slows learning. Also, it may cause transient episodes of confusion, anxiety, or even frank toxic delirium. Long term, relatively heavy use may be associated with behavioral disorders. The peak effect of smoking THC occurs in 20-30 minutes and the duration is 90-120 minutes after one cigarette. Elevated levels of urinary metabolites are found within hours of exposure and remain detectable for 3-10 days after smoking. The main metabolite excreted in the urine is 11-nor- 9-tetrahydrocannabinol-9-carboxylic acid.

PCP (Phencyclidine), also known as PCP or Angel Dust, is a hallucinogen that was first marketed as a surgical anesthetic in the 1950’s. It was removed from the market because patients receiving it became delirious and experienced hallucinations. Phencyclidine is used in powder, capsule, and tablet form. The powder is either snorted or smoked after mixing it with marijuana or vegetable matter. Phencyclidine is most commonly administered by inhalation but can be used intravenously, intra-nasally, and orally. After low doses, the user thinks and acts swiftly and experiences mood swings from euphoria to depression. Self-injurious behavior is one of the devastating effects of Phencyclidine.

9 and 10 panel drugs

Methadone is an anti-addictive medication used to treat addiction to opiates, such as heroin. Typically, this is tested for to see if an applicant may have been on heroin, or been addicted to any number of other opiates. Methadone is generally taken in pill form and is done so under the strict supervision of a physician.

BAR (Barbiturates) are central nervous system depressants. They are used therapeutically as sedatives, hypnotics, and anticonvulsants. Barbiturates are almost always taken orally as capsules or tablets. The effects resemble those of intoxication with alcohol. Chronic use of barbiturates leads to tolerance and physical dependence. Short acting Barbiturates taken at 400 mg/day for 2-3 months can produce a clinically significant degree of physical dependence. Withdrawal symptoms experienced during periods of drug abstinence can be severe enough to cause death. Only a small amount (less than 5%) of most Barbiturates are excreted unaltered in the urine.

BZO (Benzodiazepines) are medications that are frequently prescribed for the symptomatic treatment of anxiety and sleep disorders. They produce their effects via specific receptors involving a neurochemical called gamma aminobutyric acid (GABA). Because they are safer and more effective, Benzodiazepines have replaced barbiturates in the treatment of both anxiety and insomnia. Benzodiazepines are also used as sedatives before some surgical and medical procedures, and for the treatment of seizure disorders and alcohol withdrawal. Risk of physical dependence increases if Benzodiazepines are taken regularly (e.g., daily) for more than a few months, especially at higher than normal doses. Stopping abruptly can bring on such symptoms as trouble sleeping, gastrointestinal upset, feeling unwell, loss of appetite, sweating, trembling, weakness, anxiety and changes in perception. Only trace amounts (less than 1%) of most Benzodiazepines are excreted unaltered in the urine; most of the concentration in urine is conjugated drug. The detection period for the Benzodiazepines in the urine is 3-7 days.

Propoxyphene is a narcotic analgesic C22H29NO2 structurally related to methadone but less addicting that is administered especially in the form of its salts (as the hydrochloride).

Meth (Methamphetamine) is a potent sympathomimetic agent with therapeutic applications. The drug can be taken orally, injected, or inhaled. Acute higher doses lead to enhanced stimulation of the central nervous system and induce euphoria, alertness, reduced appetite, and a sense of increased energy and power. Cardiovascular responses to MET include increased blood pressure and cardiac arrhythmias. More acute responses include anxiety, paranoia, hallucinations, psychotic behavior, and eventually, depression and exhaustion. The effects of MET generally last 2-4 hours, and the drug has a half-life of 9-24 hours in the body. MET is excreted in the urine primarily as amphetamine and oxidized and deaminated derivatives. However, 10-20% of MET is excreted unchanged. Thus, the presence of the parent compound in the urine indicates MET use. MET is generally detectable in the urine for 3-5 days, depending on urine pH level.

Drug Testing Cutoff Levels

Test 

 Calibrator 

Cut off

Cocaine (COC)

Benzoylecgonine

300 ng/mL

Amphetamine (AMP)

D-Amphetamine

1,000 ng/mL

Methamphetamine (mAMP)

D-Methamphetamine

1,000 ng/mL

Marijuana (THC)

  11-nor-∆9-THC-9 COOH

50 ng/mL

Opiates (OPI 2000)

 Morphine

2,000 ng/mL

Phencyclidine (PCP)

Phencyclidine

25 ng/mL

Benzodiazepines (BZO)

Oxazepam

300 ng/mL

Tricyclic Antidepressants (TCA)

Nortriptyline

1,000 ng/mL

Barbiturates (BAR)

Secobarbital

300 ng/mL

Methadone (MTD

Methadone

300 ng/mL